Systemic intoxication can result from exposure via skin absorption or inhalation. Which of the following is true?

Systemic intoxication can result from exposure via skin absorption or inhalation. Which of the following is true?

• A. True
• B. False
• C. Only by ingestion
• D. Not related to exposure

Answer: (A)

Systemic intoxication happens when a chemical enters the bloodstream and affects tissues throughout the body, not just at the contact site. Both skin absorption and inhalation can deliver substances into the blood, allowing them to reach organs like the liver, nervous system, or heart and cause toxicity. Inhaled vapors or aerosols and dermally absorbed compounds can produce systemic effects depending on exposure concentration, duration, chemical properties (volatility, solubility, lipophilicity), and skin condition. Ingestion is another route that can cause systemic toxicity, but it isn’t the only way. So the statement is true.

Systemic intoxication happens when a chemical enters the bloodstream and affects tissues throughout the body, not just at the contact site. Both skin absorption and inhalation can deliver substances into the blood, allowing them to reach organs like the liver, nervous system, or heart and cause toxicity. Inhaled vapors or aerosols and dermally absorbed compounds can produce systemic effects depending on exposure concentration, duration, chemical properties (volatility, solubility, lipophilicity), and skin condition. Ingestion is another route that can cause systemic toxicity, but it isn’t the only way. So the statement is true.